Antibacterial Medications for Fish

Kanamycin Sulfate 100%

Kanamycin Sulfate 

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  100 gram $69.75
  200 gram (Bulk) $105.75


Use for systemic infections (septicemia), dropsy, whirling disease, kidney disease.

Dose at 1/2 tsp per 10 gallons. Re-treat every 48 hours for 10 days. Do a minimum 25% water change before each retreatment. Kanamycin Sulfate is one of the only antibiotics that is easily absorbed through the skin, so is frequently used for internal problems. It's an aminoglycoside that works on many gram negative and some gram positive bacteria. Especially good for aerobic gram negative bacteria like columnaris. It works well in saltwater and higher pH. Combines well with Nitrofurazone or Bifuran. Some prefer to make an ultra broad spectrum treatment for bacteria, by combining Kanamycin Sulfate, Bifuran and Metronidazole. For ornamental fish use only.


Neomycin Sulfate 100%

Kanamycin Sulfate 

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  100 gram $29.75
  500 gram (Bulk) $135.75


Broad spectrum antibiotic that is affective against many bacterial infections and enteritis.  Will also treat some forms of Pseudomonas and occasionally Mycobacterium tuberculosis.

Dose at 1/2 tsp per 10 gallons. Re-treat every 24 hours for 10 days. Do a minimum 25% water change before each retreatment.  Neomycin Sulfate is not absorbed by the intestinal tract and therefore is effective in treating diseases of the intestinal tract. For ornamental fish use only.


Oxytetracycline Hydrochloride 100%

Oxytetracycline Hydrochloride 

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  100 gram $17.75
  500 gram (Bulk) $63.75


Use for fin/tail rot, septicemia, popeye and secondary infections.

Dose at 1 tsp per 10-50 gallons depending on severity of infection. Re-treat every 24 hours for 10 days. Do a minimum 25% water change before each retreatment. Oxytetracycline Hydrochloride is a bacteriostatic that works on a few gram negative and many gram positive bacteria. Especially good for aerobic gram positive bacteria like streptococcus and staphylococcus. Best in pH below 7.6 unless mixed in food. It is not skin absorbed. High calcium neutralizes it. It will harm nitrifying bacteria. It combines well with Kanamycin Sulfate and Metronidazole for an ultra broad spectrum treatment. For ornamental fish use only.


Nitrofurazone 100%

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  100 gram $17.75


Use for Ulcers, some Protozoans, Topical Infections, Vibrio, Aeromonas, Streptococcus (milky, peeling slime), Furunculosis in Koi carp.

Dose at 1 tsp per 65-180 gallons depending on severity of infection. Retreat every 24 hours for 10 days. Do a minimum 50% water change before each retreatment. Nitrofurazone is bacteriocidal and is effective against some gram positive bacteria and many gram negative bacteria. It is best used in lower pH. It is not skin absorbed. It combines well with Kanamycin Sulfate for a very broad spectrum antibiotic. Metronidazole can also be combined for even greater range of treatment. Do not use in the presence of invertebrates. For ornamental fish use only.


Metronidazole 100%

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  100 gram (Bulk) $27.75
  500 gram (Bulk) Out of Stock

Dose at 1/4 tsp per 20 gallons. Re-treat every 24 hours for 10 days. Do a minimum 25% water change before each retreatment. Metronidazole is effective against some anaerobic gram positive bacteria. When combined with Neomycin Sulfate, it works well for bloating of the digestive tract. Its most common use is for flagellates, but when combined with other meds, it can make for a more potent agent against many internal parasites. For ornamental fish use only.


Click for Methylene Blue Powder 100%

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After the treatment: We recommend feeding our Immune Booster Flake during treatment and for 1 week after the treatment is stopped.

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Learn more about treating for bacteria in these articles.

An Introduction to bacteria

The Gram Stain Procedure and Theory